Tepezza (teprotumumab-trbw) is an infused biologic approved by the FDA in January 2020 to treat thyroid eye disease. It was developed by Horizon Therapeutics, which Amgen acquired in October 2023. For many patients Tepezza meaningfully improved eye bulging and double vision — but a growing number reported something else: ringing in their ears and hearing…
Truvada, Viread, Atripla, Complera, and Stribild are HIV treatment and prevention medications made by Gilead Sciences that contain tenofovir disoproxil fumarate (TDF). Since 2001, millions of people have relied on TDF drugs — many taking them daily for years or decades, because consistent use is essential to controlling or preventing HIV. Why Are Truvada and…
GLP-1 receptor agonists — including Ozempic, Wegovy, Rybelsus, and Saxenda from Novo Nordisk, and Mounjaro, Zepbound, and Trulicity from Eli Lilly — have transformed diabetes care and weight loss, with tens of millions of prescriptions written. They work in part by dramatically slowing how quickly the stomach empties. Lawsuits allege that for some patients, that…
Tavneos (avacopan) is an oral medication approved by the FDA in October 2021 as an add-on treatment for severe active ANCA-associated vasculitis, a group of rare autoimmune diseases that inflame small blood vessels. It was developed by ChemoCentryx, which Amgen acquired in 2022. In 2026, Tavneos became the subject of one of the most dramatic…
Depo-Provera (depot medroxyprogesterone acetate, or DMPA) is an injectable contraceptive manufactured by Pfizer, administered every three months. It has been on the U.S. market since 1992 and has been used by millions of women, often for years at a time. It is also sold as Depo-SubQ Provera 104 and as authorized generics. Why Are Depo-Provera…
Suboxone is a prescription medication combining buprenorphine and naloxone, used to treat opioid use disorder. The sublingual film version — a strip that dissolves under the tongue or against the cheek — was introduced by Indivior and became one of the most widely prescribed addiction treatments in the country. In January 2022, the FDA issued…
Dupixent (dupilumab) is a biologic medication manufactured by Sanofi and Regeneron, approved by the FDA to treat atopic dermatitis (eczema), asthma, and several other inflammatory conditions. It works by blocking interleukin-4 and interleukin-13 signaling, two pathways involved in allergic inflammation. Since its 2017 approval, Dupixent has become one of the best-selling drugs in the world….